1. | PHYTOCHEMICAL AND GC-MS ANALYSIS OF ALCOHOLIC
EXTRACT OF LEAVES OF SENNA UNIFLORA (MILL.) |
| Sonja Jose*, A. Kavya, M. Kalaimani, S. Kalpana, R. Keerthana, N. Lakshmi |
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The scope of the study is to determine the bioactive constituents were present in the Ethanolic leaf extract of Senna
uniflora. Ethanolic leaf extracts were analyzed by using Clarus 680 GC-MS. The results of GC-MS analysis estimate the
presence of fifteen compounds in Ethanolic leaf extract of Senna uniflora and the most available compounds are Squalene
(13.455%). It is used as an Antiagining, anti-inflammatory, antidermittic, anticoronary, and vasodilator. N-Hexadecanoic
acid(5.8%),oxirane,tertacedyl(5.8%),(Z)6,(Z)9-pentadecadien1-ol(8.1%),Bicyclo[4.1.0]Heptane,7-Pentyl(5.1%), used as an
Antimicrobial, Anti-Inflammatory agents
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2. | NOVEL METHOD FOR SIMULTANEOUS DETERMINATION OF
TINIDAZOLE AND OFLOXACIN IN TABLET DOSAGE FORM BY
RP- HPLC METHODS |
| Neelima M*, Hudson Philip, Chinnamanan V, Dharmadurai M, Dhivakar T |
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Validation is a process that comprises validating or showing that a method/system/analyst generates accurate and
reproducible findings within a known and set range through laboratory testing. The purpose of this study is to create a method
for analysing Tinidazole and Oflaxacin pills simultaneously utilising reverse phase high performance liquid chromatography.
A simple, accurate, and exact approach for simultaneous measurement of Tinidazole and Ofloxacin in pharmaceutical dose
form has been established. The devised approach was validated in accordance with ICH standards. Tinidazole and Ofloxacin
had a percentage recovery of 100.51 and 100.73 percent, respectively, using RP-HPLC. The advantages stem from the ease
with which samples are prepared and the cheap cost of the chemicals utilised. The HPLC settings provided here enable
adequate resolution and exact quantification of the chemicals. The findings of statistical analysis of the experimental data
indicated that they were of acceptable precision and repeatability. Thus, the suggested HPLC technique may be utilised to
analyse Tinidazole and Ofloxacin in pharmaceutical dose form on a regular basis
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3. | EVALUATION OF VALSARTAN TABLETS ON LIQUID CHROMATOGRAPHY – UV SPECTROSCOPY AND ITS DISSOLUTION & DISINTEGRATION STUDIES |
| Dr. Selvakumar S*, Dr. Ravichandran S, Harish Kumar G, Dinesh Kumar K, Agil Kumar M, Udhayasri A |
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The Liquid Chromatography determination of Valsartan Tablets was performed by using water, acetonitrile and 1% glacial acetic acid solvent system as mobile phase / isocratic elution technique. The dissolution and disintegration studies were evaluated by using potassium buffer pH 6.8. The UV-Spectroscopic determination performed by using potassium buffer pH 6.8 as solvent absorbance maximum detection at 273 nm. The Valzaar- 40 mg Tablets and standard Valsartan pure drug assay was evaluated and compared by UV-Spectroscopy & isocratic elution technique, high performance liquid Chromatography methods. The content and percentage purity results were comparable for both UV-Spectroscopy and Liquid Chromatography (HPLC) methods are showed appreciable accuracy & precision values
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4. | POTENTIAL OF HERBS TOWARDS WOUND HEALING: A COMPREHENSIVE REVIEW |
| Vandana P, Chandu K, Vandana Sri K, G. Prem Sai, Lokesh Kumar C, Avinash Kumar Reddy G
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Following an injury, a wound is an anatomical and functional disturbance of the skin. Wound healing is a complicated process of tissue repair or remodelling that occurs in response to an injury. Plants and plant-derived elements have long been used to treat and manage many kinds of wounds. Different kinds of biopolymers are now being studied in order to establish a cost-efficient, long-lasting, stable, and effective delivery method for wound therapy. The purpose of this study is to compile a list of medicinal plants that have been shown to be beneficial in the treatment of wounds. Plant constituent-based wound dressings have also been thoroughly discussed, with patented formulations from various inventors included
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